Xin Long Selected Research

Neoplasms (Cancer)

5/2022	PA2G4 promotes the metastasis of hepatocellular carcinoma by stabilizing FYN mRNA in a YTHDF2-dependent manner.
1/2022	Local Release of TGF-β Inhibitor Modulates Tumor-Associated Neutrophils and Enhances Pancreatic Cancer Response to Combined Irreversible Electroporation and Immunotherapy.
1/2022	Pan-Cancer Study of SHC-Adaptor Protein 1 (SHC1) as a Diagnostic, Prognostic and Immunological Biomarker in Human Cancer.
1/2022	Response of Scalp and Skull Metastasis to Anti-PD-1 Antibody Combined with Regorafenib Treatment in a Sorafenib-Resistant Hepatocellular Carcinoma Patient and a Literature Review.
2/2021	Computer-aided screening for suppressor of variegation 4-20 homolog 1 inhibitors and their preliminary activity validation in human osteosarcoma.
1/2021	Clearable Nanoparticles for Cancer Photothermal Therapy.
12/2019	Atovaquone is active against AML by upregulating the integrated stress pathway and suppressing oxidative phosphorylation.
1/2019	Screening of novel histone deacetylase 7 inhibitors through molecular docking followed by a combination of molecular dynamics simulations and ligand-based approach.
2/2018	In silico identification of small molecules as novel LXR agonists for the treatment of cardiovascular disease and cancer.
1/2018	Structure-based discovery of new maternal embryonic leucine zipper kinase inhibitors.

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Xin Long Research Topics

Disease

14	Neoplasms (Cancer) 05/2022 - 09/2015
4	Hepatocellular Carcinoma (Hepatoma) 05/2022 - 10/2016
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2017 - 04/2005
3	Neoplasm Metastasis (Metastasis) 05/2022 - 10/2016
3	Carcinogenesis 05/2022 - 02/2021
3	Liver Cirrhosis (Hepatic Cirrhosis) 02/2020 - 01/2015
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2019 - 10/2015
2	Infections 07/2020 - 07/2019
2	Schistosomiasis (Bilharziasis) 11/2017 - 01/2015
2	Atherosclerotic Plaque (Atheroma) 01/2017 - 06/2010
2	Atherosclerosis 01/2017 - 06/2010
2	Pathologic Constriction (Stenosis) 08/2010 - 06/2010
2	Hypertension (High Blood Pressure) 02/2010 - 04/2005
1	Macular Edema 10/2022
1	Cataract (Cataracts) 10/2022
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022
1	Carcinoma (Carcinomatosis) 07/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 02/2021
1	Ulcerative Colitis 01/2021
1	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 10/2020
1	Hypersensitivity (Allergy) 10/2020
1	Coma (Comas) 07/2020
1	Streptococcal Infections (Streptococcal Infection) 07/2020
1	Gestational Diabetes (Gestational Diabetes Mellitus) 05/2020
1	Hyperbilirubinemia 05/2020
1	Breast Neoplasms (Breast Cancer) 03/2020
1	Portal Hypertension 02/2020
1	Subphrenic Abscess (Subdiaphragmatic Abscess) 01/2020
1	Fever (Fevers) 01/2020
1	Abscess 01/2020
1	Pleural Effusion (Pleural Effusions) 01/2020
1	Arthritis (Polyarthritis) 01/2020
1	COVID-19 01/2020
1	Thrombosis (Thrombus) 01/2020
1	Liver Neoplasms (Liver Cancer) 10/2016
1	Fatigue 01/2016
1	Disease Progression 11/2015
1	Poisoning 11/2015
1	Hepatolenticular Degeneration (Wilson's Disease) 11/2015
1	Body Weight (Weight, Body) 11/2015

Drug/Important Bio-Agent (IBA)

5	Proteins (Proteins, Gene)FDA Link 05/2022 - 12/2010
3	Pharmaceutical PreparationsIBA 02/2021 - 01/2016
2	Messenger RNA (mRNA)IBA 05/2022 - 12/2010
2	CytokinesIBA 02/2021 - 11/2017
2	Glucose (Dextrose)FDA LinkGeneric 05/2020 - 02/2018
2	Adenosine (Adenocard)FDA LinkGeneric 12/2010 - 06/2009
2	CholesterolIBA 06/2010 - 04/2005
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	6- (2- tert- butyl- 5- (6- methylpyridin- 2- yl)- 1H- imidazol- 4- yl)quinoxalineIBA 01/2022
1	regorafenibIBA 01/2022
1	Sorafenib (BAY 43-9006)FDA Link 01/2022
1	AntigensIBA 01/2022
1	Glutathione (Reduced Glutathione)IBA 01/2022
1	Silicon Dioxide (Silica)FDA LinkGeneric 01/2022
1	sintilimabIBA 01/2022
1	Papillomavirus Vaccines (HPV Vaccines)IBA 07/2021
1	EnzymesIBA 02/2021
1	Histone-Lysine N-MethyltransferaseIBA 02/2021
1	Circular RNAIBA 01/2021
1	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 10/2020
1	Peptide Hydrolases (Proteases)FDA Link 07/2020
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 07/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 07/2020
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 05/2020
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 05/2020
1	Ferritins (Ferritin)IBA 01/2020
1	Dacarbazine (DIC)FDA LinkGeneric 01/2020
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2020
1	Interleukin-8 (Interleukin 8)IBA 01/2020
1	Interleukin-6 (Interleukin 6)IBA 01/2020
1	Warfarin (Coumadin)FDA LinkGeneric 01/2020
1	Atovaquone (Mepron)FDA Link 12/2019
1	AntibodiesIBA 07/2019
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2019
1	Phosphotransferases (Kinase)IBA 01/2018
1	Focal Adhesion Protein-Tyrosine KinasesIBA 01/2018
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2018
1	CarcinogensIBA 12/2017
1	Mitoxantrone (Novantrone)FDA LinkGeneric 10/2017
1	Etoposide (VP 16)FDA LinkGeneric 10/2017
1	Histamine (Histamine Dihydrochloride)FDA Link 01/2017
1	Spironolactone (Aldactone)FDA LinkGeneric 01/2017
1	CalciumIBA 01/2017
1	TRPC6 Cation ChannelIBA 01/2017
1	Chlorpyrifos (Lorsban)IBA 11/2015
1	CopperIBA 11/2015

Therapy/Procedure

6	Therapeutics 01/2022 - 10/2016
4	Stents 12/2010 - 02/2010
2	Immunotherapy 01/2022 - 01/2022
2	Splenectomy 02/2020 - 10/2016
1	Phacoemulsification 10/2022
1	Photothermal Therapy 01/2021
1	Glycemic Control 05/2020
1	Radiotherapy 03/2020
1	Hepatectomy 01/2020
1	Drug Therapy (Chemotherapy) 10/2017
1	Chelation Therapy (Therapy, Chelation) 11/2015
1	Liver Transplantation 11/2015
1	Transplantation 11/2015
1	Hemoperfusion 11/2015